Fig. 1
From: Boolean network modeling of β-cell apoptosis and insulin resistance in type 2 diabetes mellitus
Gene Regulatory Network. Insulin resistance and β-cell apoptosis pathways involved in the pathogenesis of Type 2 diabetes mellitus. The red nodes denote the five input signals and the purple node represents β-cell apoptosis. A → B indicates activation of gene B by gene A, and A −| B indicates inhibition of gene B by gene A