Fig. 3

Regeneration profile showing directional change in the recovery for representative parameters belonging to different classes. Parameter value increases in the order of color scheme shown in the color bar. a, b, c Only recovery occurs, which improves with increasing kGF (a), deteriorates with increasing κJAK (b), and is insensitive to increase in κST3 (c). d, e, f Both recovery and failure occur, and are sensitive to changes in M (d) and βap (e), insensitive to changes in θap