Fig. 4

Relative cytokine levels discriminating between uniphasic and biphasic viremia profiles over infection time. Relative cytokine levels discriminating between uniphasic and biphasic viremia profiles over infection time. Percentage of a antiviral cytokines (IFNγ,IFNα,TNFα) among antiviral and immuno-modulatory (IL10,TGFβ) cytokines; b IFNγ and c IFNα among antiviral cytokines; d pro-cellular (IL12,IFNγ) and e pro-humoral (IL4,Pi) cytokines over the pro-cellular, pro-humoral and pro-regulatory (TGFβ) cytokines. Mean value (solid line) and standard deviation (shaded area) of the 35 representative individuals selected for the uniphasic (green) and biphasic (red) profiles; Balanced contribution level (horizontal dashed line). ∗p-value <5% when comparing uniphasic and biphasic profiles (permutation tests over four time periods: 0–10, 11–20, 21–31, 32–42 days)